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. 2018 Jan 17;13(1):e0190418. doi: 10.1371/journal.pone.0190418

Fig 2. Sequence alignment of Msp2 FC27 family of Plasmodium falciparum showing the polymorphisms in each block.

Fig 2

Changes of nt. / aa. are shaded with gray / yellow. The Msp2 sequence of K1 (FC27-liked) (GenBank accession number: M59766.1) was used as a reference for Block 2 and 4 alignment. (A) Block 2: the first 6 nt. residues of 57 (19 aa.) were not analyzed. An indel and 7 non-synonymous SNPs are shown. (B) Block 4: only the first 90 nt. residues of 144 (48 aa.) are presented. Two non-synonymous SNPs are shown. (C) Block 3, repeat region1 (R1): only the first 90 nt. residues of the 96 nt. repeat are presented, showing 4 repeat variants (R1-A, R1-B, R1-C, R1-D) with different positions of single non-synonymous SNPs. (D) Block 3, repeat region2 (R2): 36 nt. repeat showing 3 repeat variants (R2-1, R2-2, R2-3) with different non-synonymous SNPs.