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. 2018 Jan 17;13(1):e0190418. doi: 10.1371/journal.pone.0190418

Fig 3. Sequence alignment of Msp2 3D7 family of Plasmodium falciparum showing polymorphisms in each block.

Fig 3

Changes in nt. / aa. are shaded gray / yellow. The Msp2 sequence for 3D7 (GenBank accession number: PFB0300c) was used as a reference for alignment of Block 2, 4, and the non-repetitive region (NR) of block 3. (A) Block 2: first 6 nt. residues of 21 (7 aa.) are not analyzed. Four non-synonymous SNPs are shown. (B) Block 4: only residues from nt. 31 to 100 of 270 (90 aa.) are presented. Eight non-synonymous SNPs and 2 indel are shown. (C) Block 3, non-repeat region (NR): all 54 nt. (18 aa.) are presented, showing 6 non-synonymous SNPs and 3 indel. (D) Block 3, repeat region 2 (R2): 2, 3, and 4 copies of nanomer (ACT ACC ACA) followed by ACT ACT producing Threonine 8, 11, and 14 residues, respectively.