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. 2018 Jan 17;13(1):e0189582. doi: 10.1371/journal.pone.0189582

Fig 1. Heat map showing up-regulated and down-regulated differentially expressed genes (DEGs) in bevacizumab-resistant colon cancer tumors.

Fig 1

A bidirectional hierarchical clustering heat map was constructed using MultiExperimental Viewer(MeV). The expression values are log2 fold changes (>1 or <−1, FDR <0.05)) between corresponding bevacizumab -resistant HT29 xenograft tumors and non-treated HT29 xenograft tumors. Black represents no change in expression, green represents down-regulation, and red represents up-regulation.