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. 2018 Jan 17;13(1):e0189582. doi: 10.1371/journal.pone.0189582

Fig 4. Kaplan-Meier survival curves presenting the prognostic relationship between high and low expression of specific genes involved in bevacizumab resistance to overall survival (OS) in TNM clinical stage 3 and 4(A) PDGFA, (B) BRCA1, (C) TLR4, (D) MMP1 (E) CD19 and (F) CDKN1A expression.

Fig 4

The survival curves were plotted using the survExpress online tool. The specific DEGs expression levels were dichotomized by median value and stratified for TNM clinical stage. The results presented visually by Kaplan-Meier survival plots. p-values were calculated using log-rank statistics. Patient number(N) = 270, p = Logrank p-value.