Table 2. Down-regulated genes which had interactions in the PPIs.

Gene symbol	Gene name	Degree	Betweenness
BRCA1	breast cancer 1, early onset	35.0	326.96054
FANCD2	fanconi anemia complementation group D2	19.0	33.54729
RBL1	retinoblastoma-like 1 (p107)	13.0	12.75956
TLR4	toll-like receptor 4	8.0	31.75171
GINS4	GINS complex subunit 4	4.0	0.0
CD19	CD19 molecule	2.0	0.0
HEATR1	HEAT repeat containing 1	2.0	0.0
PSMB11	proteasome subunit beta 11	2.0	0.0
BLVRA	biliverdin reductase A	2.0	0.0