Fig 3. Effects of diet manipulation and 1,25 (OH)₂ vitamin D supplementation on oral glucose tolerance test and HOMA index measured at the end of the experimental protocol (week 16) in fasted animals.

Panel A. Oral glucose tolerance test (OGTT). Values are means ± S.E.M. of 6–10 animals per group. Statistical analysis was performed with Two-way analysis of variance with Bonferroni's post-hoc test. *p<0.05, ***p<0.001 vs Control; ^#p<0.05, ^##p<0.01, ^###p<0.001 vs HFHS. Panel B. HOMA index. Data are expressed by medians and interquartile range of 4–6 animals randomly selected per group. Statistical analysis was performed with Kruskal–Wallis test with Dunn’s post hoc test. *p<0.05 vs Control; ^#p<0.05 vs HFHS.