Table 4. Most frequently reported treatment emergent adverse events and serious adverse events, as reported in clinical study report.

	doxylamine-pyridoxine (n = 133)	Placebo (n = 128)	p-value
Headache	17 (12.8%)	20 (15.6%)	0.51
Somnolence	19 (14.2%)	15 (11.7%)	0.58
Fatigue	9 (6.8%)	8 (6.3%)	0.86
Dizziness	8 (6.0%)	8 (6.3%)	0.94
Back pain	7 (5.3%)	4 (3.1%)	0.39
Serious
Bile duct stone	0	1 (0.8%)	0.49
Missed abortion	1 (0.8%)	1 (0.8%)	1.0
Spontaneous abortion	2 (1.5%)	1 (0.8%)	0.49
Fetal disorder	0	1 (0.8%)	0.49
Intrauterine death	1 (0.8%)	0	1.0
Premature rupture of membranes	0	1 (0.8%)	0.49
Withdrawals
Withdrawals due to adverse events	5 (3.8%)	5 (3.9%)	-