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. 2018 Jan 17;13(1):e0191026. doi: 10.1371/journal.pone.0191026

Fig 3. Hepatic gene expression levels involved in immune response pathway or TLR4 signaling.

Fig 3

In 20 patients (non-alcohol group: 10, light alcohol consumer group: 10), the expression levels of genes were measured using RT-PCR, and evaluated using the Mann-Whitney U test. The expression levels of PSMB9 and Icam1 were significantly higher in the non-alcohol group than in the light alcohol consumer group. There was also a trend of decreased expression levels of TLR4 and other genes among patients in the light alcohol consumer group. Notes: TLR4, toll like receptor (TLR) 4; STAT3, signal transducer and activator of transcription 3; NFκB, nuclear factor-kappa beta; Ccl5, CC chemokine ligand 5; Pecam1, Platelet endothelial cell adhesion molecule; CD44, cluster of differentiation 44; PSMB9,Proteasome subunit beta type-9 (PSMB9); Icam1, intercellular adhesion molecule-1.