Table 1. The values of perfusion and diffusion parameters from the tumor core in GBMs, metastases and PCNSLs with the analysis of variance and multiple post-hoc comparisons among the patient subgroups.
| Parameters evaluated (MR technique) |
Mean value ± SD (range) |
ANOVA p values |
Scheffe test, p values | ||||
|---|---|---|---|---|---|---|---|
| GBM | META | PCNSL | GBM vs META | GBM vs PCNSL | META vs PCNSL | ||
| mean rCBV (PWI) |
3.10±1.50 (1.11–6.89) |
4.49±3.94 (1.80–14.88) |
0.80±0.35 (0.31–1.41) |
0.0001 | 0.23 | 0.032 | 0.0001 |
| max rCBV (PWI) |
7.65±4.75 (2.09–19.30) |
7.53±5.38 (2.50–18.76) |
1.32±0.58 (0.44–2.18) |
0.0001 | 0.99 | 0.0001 | 0.0001 |
| mean rPH (PWI) |
2.79±1.29 (1.26–6.45) |
3.15±2.01 (1.54–8.88) |
1.16±0.40 (0.74–2.40) |
0.0001 | 0.73 | 0.006 | 0.001 |
| max rPH (PWI) |
5.55±2.93 (1.27–12.39) |
5.23±2.90 (2.57–12.16) |
1.79±0.73 (0.86–3.69) |
0.0001 | 0.91 | 0.0001 | 0.001 |
| mean rPSR (PWI) |
1.17±0.28 (0.79–2.08) |
1.19±0.64 (0.50–3.50) |
1.92±0.75 (1.22–3.78) |
0.0001 | 0.99 | 0.001 | 0.002 |
| max rPSR (PWI) |
1.32±0.40 (0.87–2.73) |
1.30±0.65 (0.59–3.50) |
2.29±0.19 (1.24–5.83) |
0.0001 | 0.99 | 0.002 | 0.002 |
| mean ADC* (DWI) |
1.02±0.17 (0.69–1.47) |
1.03±0.19 (0.73–1.34) |
0.73±0.13 (0.57–1.04) |
0.0001 | 0.98 | 0.0001 | 0.0001 |
| min ADC* (DWI) |
0.72±0.15 (0.47–1.13) |
0.76±0.20 (0.46–1.18) |
0.57±0.12 (0.40–0.82) |
0.002 | 0.73 | 0.024 | 0.003 |
*ADC values should be multiplied by 10−3 and expressed in units of mm2/s.
ADC, apparent diffusion coefficient; DWI, diffusion weighted imaging; GBM, glioblastoma multiforme; META, metastasis; max, maximum; min, minimum; PCNSL, primary CNS lymphoma; PWI, perfusion weighted imaging; rCBV, relative cerebral blood volume; rPH, relative peak height; rPSR, relative percentage of signal recovery.