Table 2. The results of ROC analysis for differentiation of PCNSLs from GBMs and metastases as well as GBMs from metastases.

PCNSLs vs (GBMs + metastases)
Parameter	Accuracy	Cut-off value	Specificity	Sensitivity
mean rCBV	0.984	< 1.41	0.975	1.0
max rCBV	0.985	< 2.18	0.975	1.0
mean rPH	0.969	< 1.49	0.975	0.938
max rPH	0.938	< 3.01	0.875	0.938
mean rPSR	0.860	> 1.39	0.875	0.813
max rPSR	0.851	> 1.65	0.725	0.875
mean ADC*	0.903	< 0.81*	0.850	0.875
min ADC*	0.777	< 0.56*	0.850	0.625
GBMs vs metastases
Parameter	Accuracy	Cut-off value	Specificity	Sensitivity
mean rCBV	0.911	> 0.6	0.85	0.85
max rCBV	0.940	> 0.98	1.0	0.9
mean rPH	0.699	> 0.94	0.5	0.85
max rPH	0.763	> 2.05	0.85	0.65
mean rPSR	0.573	< 0.99	0.85	0.35
max rPSR	0.538	< 1.13	0.85	0.35
mean ADC*	0.628	< 1.49*	0.85	0.55
min ADC*	0.721	< 1.1*	0.9	0.65

*ADC values should be multiplied by 10⁻³ and expressed in units of mm²/s.

ADC, apparent diffusion coefficient; GBM, glioblastoma multiforme; max, maximum; min, minimum; PCNSL, primary CNS lymphoma; rCBV, relative cerebral blood volume; rPH, relative peak height; rPSR, relative percentage of signal recovery.