Table 3. The values of perfusion and diffusion parameters from the peritumoral zone in GBMs and metastases with the comparisons between the patient subgroups.
Parameters evaluated (MR technique) |
Mean value ± SD (range) |
p values | |
---|---|---|---|
GBM | META | ||
mean rCBV (PWI) |
1.05±0.39 (0.56–1.89) |
0.55±0.13 (0.35–0.77) |
0.0001 |
max rCBV (PWI) |
2.07±0.75 (0.70–3.75) |
0.78±0.15 (0.53–0.98) |
0.0001 |
mean rPH (PWI) |
1.27±0.38 (0.59–1.96) |
1.01±0.36 (0.43–1.77) |
0.035 |
max rPH (PWI) |
2.22±0.84 (0.76–3.84) |
1.53±0.56 (0.66–2.71) |
0.004 |
mean rPSR (PWI) |
1.15±0.25 (0.76–1.62) |
1.21±0.20 (0.89–1.58) |
0.414 |
max rPSR (PWI) |
1.40±0.35 (0.90–2.19) |
1.44±0.36 (1.07–2.58) |
0.740 |
mean ADC* (DWI) |
1.47±0.27 (0.99–1.90) |
1.58±0.15 (1.16–1.79) |
0.123 |
min ADC* (DWI) |
1.07±0.32 (0.60–1.62) |
1.31±0.13 (0.99–1.48) |
0.005 |
*ADC values should be multiplied by 10−3 and expressed in units of mm2/s.
ADC, apparent diffusion coefficient; DWI, diffusion weighted imaging; GBM, glioblastoma multiforme; META, metastasis; max, maximum; min, minimum; PWI, perfusion weighted imaging; rCBV, relative cerebral blood volume; rPH, relative peak height; rPSR, relative percentage of signal recovery.