Table 2. The 82-transcript intracranial aneurysm-associated gene expression signature*.
| Transcript | Gene ID | Accession No. | Log2(F-C) | P-Value | Q-Value |
|---|---|---|---|---|---|
| MAOA | 4128 | M69226.1 | 5.56 | 0.03455 | 0.9999 |
| C21orf15 | 54055 | AY040090.1 | 2.38 | 0.00005 | 0.0836063* |
| CYP1B1 | 1545 | NM_000104.3 | 2.02 | 0.00005 | 0.0836063* |
| ARMC12 | 221481 | NM_145028.4 | 1.95 | 0.0006 | 0.4459 |
| CD177 | 57126 | NM_020406.3 | 1.81 | 0.001 | 0.585244 |
| OLAH | 55301 | NM_018324.2 | 1.79 | 0.0057 | 0.9999 |
| CYP1B1-AS1 | 285154 | NR_027252.1 | 1.73 | 0.004 | 0.9999 |
| FLT3 | 2322 | NM_004119.2 | 1.63 | 0.00005 | 0.0836063* |
| CD163 | 9332 | DQ058615.1 | 1.62 | 0.0005 | 0.393441 |
| KCNMA1 | 3778 | NM_001014797.2 | 1.61 | 0.050 | 0.9999 |
| DACT1 | 51339 | NM_016651.5 | 1.60 | 0.0045 | 0.9999 |
| FAM90A1 | 55138 | NM_018088.3 | 1.58 | 0.0059 | 0.9999 |
| SCT | 6343 | AF244355.1 | 1.58 | 0.0232 | 0.9999 |
| LOC100131289 | 100131289 | NR_038929.1 | 1.54 | 0.0095 | 0.9999 |
| NOG | 9241 | NM_005450.4 | 1.52 | 0.013 | 0.9999 |
| SCAMP5 | 192683 | NM_001178111.1 | 1.52 | 0.030 | 0.9999 |
| PTGDS | 5730 | NM_000954.5 | 1.47 | 0.0052 | 0.9999 |
| KIR2DS4 | 3809 | NM_012314.5 | 1.45 | 0.014 | 0.9999 |
| CYP4F35P | 284233 | NR_026756. | 1.43 | 0.0082 | 0.9999 |
| XKR3 | 150165 | NM_001318251.1 | 1.41 | 0.00005 | 0.0836063* |
| RPL39L | 116832 | NM_052969.2 | 1.40 | 0.017 | 0.9999 |
| CDHR2 | 54825 | NM_001171976.1 | 1.35 | 0.013 | 0.9999 |
| ENHO | 375704 | NM_198573.2 | 1.35 | 0.014 | 0.9999 |
| SLC12A7 | 10723 | NM_006598.2 | 1.35 | 0.00005 | 0.0836063* |
| FLJ27354 | 400761 | NR_033981.1 | 1.34 | 0.025 | 0.9999 |
| DGKH | 160851 | NM_152910.5 | 1.33 | 0.0039 | 0.9999 |
| SDC3 | 9672 | AF248634.1 | 1.33 | 0.028 | 0.9999 |
| THBS1 | 7057 | NM_003246.3 | 1.32 | 0.0019 | 0.85336 |
| RCVRN | 5957 | NM_002903.2 | 1.30 | 0.016 | 0.9999 |
| AKR1C1 | 1645 | NM_001353.5 | 1.30 | 0.030 | 0.9999 |
| SCRG1 | 11341 | NM_001329597.1 | 1.28 | 0.027 | 0.9999 |
| NRG1 | 3084 | NM_013959.3 | 1.26 | 0.030 | 0.9999 |
| AK5 | 26289 | NM_174858.2 | 1.24 | 0.0024 | 0.9999 |
| ITGA7 | 3679 | NM_001144996.1 | 1.23 | 0.017 | 0.9999 |
| PAM | 5066 | NM_000919.3 | 1.20 | 0.00005 | 0.0836063* |
| LYPD2 | 137797 | NM_205545.2 | 1.19 | 0.028 | 0.9999 |
| PRUNE2 | 158471 | NM_015225.2 | 1.19 | 0.0009 | 0.547241 |
| SLC22A17 | 51310 | NM_020372.3 | 1.16 | 0.018 | 0.9999 |
| ADTRP | 84830 | NM_001143948.1 | 1.16 | 0.0054 | 0.9999 |
| ADAMTS1 | 9510 | NM_006988.4 | 1.15 | 0.0024 | 0.9999 |
| ECRP | 643332 | NR_033909.1 | 1.15 | 0.049 | 0.9999 |
| LOC100507387 | 100507387 | NR_038402.1 | 1.11 | 0.040 | 0.9999 |
| KLRC2 | 3822 | NM_002260.3 | 1.11 | 0.034 | 0.9999 |
| AKR1C3 | 8644 | NM_003739.5 | 1.09 | 0.0063 | 0.9999 |
| SEPT10 | 151011 | NM_144710.4 | 1.08 | 0.011 | 0.9999 |
| CYYR1 | 116159 | NM_001320768.1 | 1.08 | 0.037 | 0.9999 |
| TCL1A | 8115 | NM_021966.2 | 1.07 | 0.0024 | 0.9999 |
| VWF | 7450 | NM_000552.4 | 1.06 | 0.010 | 0.9999 |
| GNLY | 10578 | NM_001302758.1 | 1.06 | 0.0025 | 0.9999 |
| C4BPA | 722 | NM_000715.3 | 1.05 | 0.0027 | 0.9999 |
| LINC00482 | 284185 | NR_038080.1 | 1.05 | 0.048 | 0.9999 |
| KIAA1598 | 57698 | BC022348.1 | 1.04 | 0.0092 | 0.9999 |
| PID1 | 55022 | NM_017933.4 | 1.03 | 0.0090 | 0.9999 |
| SERPINF2 | 5345 | NM_000934.3 | 1.02 | 0.027 | 0.9999 |
| VWA8 | 23078 | NM_015058.1 | 1.01 | 0.0057 | 0.9999 |
| CYP4F2 | 8529 | NM_001082.4 | -1.00 | 0.039 | 0.9999 |
| FADS2 | 9415 | NM_004265.3 | -1.01 | 0.011 | 0.9999 |
| VLDLR | 7436 | NM_003383.4 | -1.03 | 0.0005 | 0.393441 |
| CARD17 | 440068 | NM_001007232.1 | -1.04 | 0.016 | 0.9999 |
| IL8 | 576 | AF043337.1 | -1.04 | 0.0001 | 0.148633* |
| G0S2 | 50486 | NM_015714.3 | -1.05 | 0.003 | 0.9999 |
| FBXW8 | 26259 | NM_153348.2 | -1.08 | 0.0007 | 0.468195 |
| MFSD9 | 84804 | NM_032718.4 | -1.08 | 0.0002 | 0.26754 |
| CCL23 | 6368 | NM_005064.5 | -1.09 | 0.019 | 0.9999 |
| C1orf226 | 400793 | NM_001135240.1 | -1.11 | 0.020 | 0.9999 |
| GBP5 | 115362 | NM_052942.3 | -1.14 | 0.001 | 0.642096 |
| BATF2 | 116071 | NM_138456.3 | -1.17 | 0.0005 | 0.393441 |
| FCRL5 | 83416 | NM_031281.2 | -1.18 | 0.013 | 0.9999 |
| SERPING1 | 710 | NM_000062.2 | -1.21 | 0.0003 | 0.334425 |
| B4GALNT3 | 283358 | NM_173593.3 | -1.26 | 0.023 | 0.9999 |
| PDCD1LG2 | 80380 | NM_025239.3 | -1.28 | 0.0029 | 0.9999 |
| FBN1 | 2200 | NM_000138.4 | -1.33 | 0.00005 | 0.0836063* |
| PRSS21 | 10942 | NM_006799.3 | -1.43 | 0.0016 | 0.797475 |
| ETV7 | 51513 | NM_016135.3 | -1.43 | 0.0005 | 0.393441 |
| SEPT4 | 5414 | NM_004574.4 | -1.46 | 0.009 | 0.9999 |
| EGR2 | 1959 | J04076.1 | -1.50 | 0.011 | 0.9999 |
| GBP1P1 | 400759 | NR_003133.2 | -1.70 | 0.0018 | 0.85336 |
| PSORS1C3 | 100130889 | AB932952.1 | -1.75 | 0.0035 | 0.9999 |
| HRK | 8739 | NM_003806.3 | -1.83 | 0.0079 | 0.9999 |
| NEB | 4703 | NM_001164507.1 | -1.98 | 0.020 | 0.9999 |
| GPC4 | 2239 | NM_001448.2 | -2.32 | 0.00005 | 0.0836063* |
| LOC730441 | 207147 | BC039387.1 | -6.77 | 0.0498 | 0.9999 |
*Significantly differentially expressed transcripts with q-value<0.20 (20% FDR) are marked by “*”.