. Author manuscript; available in PMC: 2018 Jan 17.

Published in final edited form as: Semin Perinatol. 2014 Oct 1;38(8):475–486. doi: 10.1053/j.semperi.2014.08.011

Table 1.

Transporters in the liver, kidney, small intestine, and placenta in humans.

Organs in humans	Influx transporters	Eflux transporters
Liver	NTCP, OAT2, OATP1/2, and OCT1/3 (blood side)	BCRP, BSEP MATE1, MDR1/3, and MRP2 (bile side)
Kidney	MRP1/3/5/6, OAT1/2/3, OATP4C, OCT2/3, and OST (blood side)	ASBT, BCRP, MATE1/2, MDRI, MRP2/4, OCTN1/2, OAT4, OATP1, and PEPT (urine side)
Intestine	MRP1/3, OCT1, and OST (blood side)	ASBT, BCRP, MDRI, MRP2, OATP1/2, OCT3, and PEPT (luminal side)
Placenta	MRP5, OAT4, OATP2B, and OCT3 (fetal blood side)	BCRP, MDRI, MRP1/2/3, and OATP4A (maternal blood side)

Note: ASBT, apical sodium-dependent bile acid transporter; BCRP, breast cancer resistance protein; BSEP, bile salt export pump; MATE, multidrug and toxic compound extrusion; MDR, multi-drug-resistant ABC transporter; MRP, multidrug resistance-associated protein; NTCP, sodium-taurocholate cotransporting polypeptide; OAT, organic anion transporters; OATP, organic anion-transporting polypeptide; OCT, organic cation transporters; OST, organic solute transporter; PEPT, peptide transporter.