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. Author manuscript; available in PMC: 2018 Jan 17.
Published in final edited form as: Semin Perinatol. 2014 Oct 1;38(8):475–486. doi: 10.1053/j.semperi.2014.08.011

Table 4.

Medications and dietary components used during pregnancy that are known cytochrome P450 3A4 inducers or inhibitors.

Cytochrome P450 3A4 inducers Cytochrome P450 3A4 inhibitors
Anticonvulsants (carbamazepine) Azole antifungals (ketoconazole and itraconazole)
Bactericidals (rifampicin) Antidepressants (nefazodone)
St. John’s wort Protease inhibitors (ritonavir, indinavir, nelfinavir, and saquinavir)
Grapefruit juice (bergamottin)
Macrolide antibiotics (clarithromycin and erythromycin)