Table 3. Experimental lines from (Barkoulas et al., 2013), and one line from (Hoyos et al., 2011), referred in this study.

Levels used to model the lines were based on measurements of EGF mRNA levels from (Barkoulas et al., 2013) or fit, as indicated. For combined perturbations, we indicate the corresponding single perturbations lines.

EGF perturbation lines
CB1417	lin-3(e1417) hypomorph; level included as fitting parameter ~0.28 × WT (measured as ~0.06 × WT in (Barkoulas et al., 2013) and ~0.22 × WT in [Saffer et al., 2011])
JU2036	measured as ~ 1.25 × WT
JU2035	measured as ~ 1.79 × WT
JU1107	measured as ~ 2.75 × WT
JU1100 (Hoyos et al., 2011)	level included as fitting parameter ~4.2 × WT (not measured)
Notch perturbation lines
JU2039	Pn.p cell-specific RNAi; level fit to phenotype strength ~0.4 × WT
JU2064	ectopic Notch activity; level included as fitting parameter ~WT + 0.05
JU2060	ectopic Notch activity; level fit to yield near-complete P4/8.p conversion ~ WT + 0.26
Combined perturbations
JU2113	JU2036 × JU2039
JU2091	JU2036 × JU2064
JU2089	JU2035 × JU2064
JU2092	JU1107 × JU2064
JU2095	CB1417 × JU2064