Table 2.

Modeling of cortex and cerebellum growth and degeneration

	Wild-type (WT)			Nhe6-null (MUT)
	Rate (cm2/mo)	Coefficients (mo−1)		Rate (cm2/mo)	Undergrowth-only modelCoefficients (mo−1)		Degeneration-only modelCoefficients (mo−1)
Brain region and time point	Mean	G	D	Mean	G	D	G	D
Cortex
0–1 mo	0.5092	0.6764	0	0.516	0.6737	0	0.6764	0.0027
1–2 mo	0.156	0.1712	0	0.0415	0.0514	0	0.1712	0.1198
2–6 mo	0.0101	0.0106	0	0.0248	0.0274	0	0.0106	–0.0168
6–23 mo	–0.01037	0	0.0134	–0.00922	0	0.0123	0	0.0123
Cerebellum
0–1 mo	0.1873	0.8558	0	0.1887	0.8537	0	0.8558	0.0021
1–2 mo	0.07243	0.2487	0	0.0332	0.1305	0	0.2487	0.1182
2–6 mo	0.00233	0.0078	0	0.0012	0.0047	0	0.0078	0.0031
6–23 mo	–0.00308	0	0.0124	–0.00488	0	0.0277	0	0.0277

D, Degeneration coefficient; G, Growth coefficient; mo, month or months; MUT, Nhe6-null; WT, wild-type.