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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Cancer Causes Control. 2017 Aug 16;28(10):1085–1093. doi: 10.1007/s10552-017-0938-3

Table 4.

Hazard ratios and 95% CI for all stages and T4 stage only OPC patients diagnosed in 1997, 2004 and 2009 using SEER POC (weighted data).

Hazard Ratio 95 CI)

Characteristics All Stages
n= (787)
T4 Stage Only
n= (182)
Year of diagnosis 1997 1.00 (Referent) 1.00 (Referent)
2004 0.69 (0.47, 1.01) 0.87 (0.50, 1.52)
2009 0.51 (0.33, 0.78)* 1.00 (0.55, 1.83)

Age continuous) 1.03 (1.02, 1.05)* 1.02 (0.99, 1.04)

Race Non-white 1.00 (Referent) 1.00 (Referent)
White 0.74 (0.54, 1.00) 1.04 (0.72, 1.49)

Sex Female 1.00 (Referent) 1.00 (Referent)
Male 0.94 (0.64, 1.38) 0.82 (0.57, 1.18)

Marital status Married 1.00 (Referent) 1.00 (Referent)
Unmarried 2.10 (1.51, 2.91)* 1.85 (0.96, 3.55)

Charlson Score 0 1.00 (Referent) 1.00 (Referent)
≥ 1 1.77 (1.20, 2.62)* 1.61 (0.88, 2.96)

Stage Group I, II & III 1.00 (Referent)
(AJCC 6th Ed.) IVA & IVB 1.37 (0.83, 2.26) 1.00 (Referent)
IVC 2.22 (1.16, 4.26)* 5.64 (3.00, 10.58)*
Unknown 1.25 (0.72, 2.17) 0.19 (0.13, 1.06)

Type of Therapy Surgery 1.00 (Referent) 1.00 (Referent)
RTC 1.42 (0.93, 2.17) 0.71 (0.37, 1.38)

Hospital Beds 1–299 /Unknown 1.00 (Referent) 1.00 (Referent)
≥ 300 1.24 (0.90, 1.71) 1.38 (0.77, 2.48)
*

Significant at α = 0.05

OPC=oropharyngeal cancer