Table 2.
Mixed model results for PROMIS Pediatric symptoms
| Fatigue | Pain Interference | Anger | Anxiety | Depressive Symptoms | |
|---|---|---|---|---|---|
| Intercept (adjusted^) | 51.9 (47.8, 55.9) | 49.3 (45.9, 52.8) | 46.4 (41.3, 51.5) | 47.7 (44.0, 51.3) | 50.3 (47.1, 53.6) |
| T1 (baseline) | −3.1** (−5.3, −0.9) | −2.6** (−4.4, −0.7) | 1.0 (−1.1, 3.0) | 0.2 (−1.5, 1.9) | 0.9 (−0.7, 2.4) |
| T3 (recovery) | −6.4*** (−8.3, −4.5) | −5.5*** (−7.1, −3.9) | −3.3** (−5.5, −1.1) | −4.3*** (−5.7, −2.9) | −3.7*** (−5.05, −2.43) |
| T4 (follow-up) | −6.1*** (−8.3, −3.9) | −4.0*** (−5.8, −2.1) | −2.0 (−4.9, 1.0) | −3.3*** (−4.9, −1.6) | −2.9*** (−4.46, −1.37) |
| Female | 3.4** (0.9, 6.0) | 1.9 (−0.2, 4.0) | 2.0 (−1.3, 5.4) | 1.6 (−0.7, 3.9) | 0.4 (−1.58, 2.47) |
| Age | 0.3 (−0.2, 0.7) | 0.1 (−0.2, 0.5) | −0.3 (−0.8, 0.3) | −0.3 (−0.7, 0.1) | −0.1 (−0.45, 0.24) |
| 1+ conditions | −1.2 (−3.9, 1.4) | 1.1 (−1.1, 3.4) | −1.7 (−5.3, 1.9) | −1.5 (−4.0, 0.9) | −0.4 (−2.58, 1.75) |
| Not White | −1.7 (−4.7, 1.2) | −0.2 (−2.7, 2.3) | −3.0 (−7.7, 1.8) | −2.5 (−5.2, 0.3) | −2.7* (−5.11, −0.35) |
| Hispanic | 3.4 (−0.9, 7.7) | 1.2 (−2.5, 4.8) | 3.9 (−1.8, 9.6) | 3.4 (−0.6, 7.4) | 1.3 (−2.17, 4.83) |
| H.S. or less | 1.9 (−0.8, 4.6) | 2.5* (0.2, 4.8) | 1.7 (−2.2, 5.5) | 1.8 (−0.7, 4.2) | 1.8 (−0.40, 3.95) |
| Incident NS | −3.3* (−6.5, −0.1) | −1.6 (−4.3, 1.1) | 2.1 (−0.8, 5.0) | 0.2 (−2.3, 2.8) | |
| Sickle Cell | 2.2 (−1.5, 5.9) | 5.7*** (2.6, 8.9) | −0.7 (−5.1, 3.7) | 0.2 (−3.2, 3.6) | −1.5 (−4.5, 1.5) |
| Model R2 | 0.16 | 0.17 | 0.10 | 0.14 | 0.14 |
| Observations | 744 | 743 | 442 | 740 | 744 |
| Log Likelihood | −2,889.4 | −2,756.7 | −1,658.9 | −2,715.5 | −2,663.1 |
| AIC | 5,806.8 | 5,541.4 | 3,343.9 | 5,459.1 | 5,354.1 |
| BIC | 5,871.4 | 5,605.9 | 3,397.0 | 5,523.5 | 5,418.7 |
Note:
*
p<0.05;
**
p<0.01;
***
p<0.001;
AIC = Akaike information criteria; BIC = Bayesian Information Criteria,
^
The intercept can be interpreted as the mean symptom score at T2 (event) for the reference group who are non-Hispanic white, 8-year old boys with cancer, no other health condition and a mother with education more than high school.