Table 3.
Mixed model results for PROMIS Pediatric function domains
| Mobility | Upper Extremity | Peer Relationships | |
|---|---|---|---|
| Intercept (adjusted^) | 40.4 (37.5, 43.3) | 42.5 (39.0, 45.9) | 47.7 (44.5, 51.0) |
| T1 (baseline) | 2.8*** (1.3, 4.4) | 3.0*** (1.3, 4.8) | 1.8* (0.2, 3.5) |
| T3 (recovery) | 3.7*** (2.4, 5.0) | 3.1** (1.2, 5.0) | 1.6* (0.2, 3.0) |
| T4 (follow-up) | 5.3*** (3.8, 6.8) | 5.6*** (3.0, 8.1) | 2.0* (0.4, 3.7) |
| Female | −1.7 (−3.5, 0.1) | −4.0*** (−6.3, −1.8) | −0.1 (−2.1, 2.0) |
| Age | −0.1 (−0.4, 0.2) | 0.6** (0.2, 1.0) | 0.6** (0.2, 0.9) |
| 1+ Conditions | −0.8 (−2.7, 1.1) | 0.6 (−1.8, 3.0) | −1.5 (−3.7, 0.7) |
| Not White | 1.5 (−0.7, 3.6) | 1.5 (−1.6, 4.6) | −2.2 (−4.6, 0.2) |
| Hispanic | −1.0 (−4.1, 2.1) | −3.1 (−6.9, 0.6) | −1.4 (−4.9, 2.1) |
| High school or less | −1.3 (−3.2, 0.7) | −0.8 (−3.4, 1.8) | −2.5* (−4.7, −0.3) |
| Incident NS | 7.4*** (5.2, 9.7) | ---- | 1.6 (−0.9, 4.2) |
| Sickle Cell | 4.3** (1.7, 7.0) | 0.4 (−2.6, 3.3) | −0.3 (−3.3, 2.7) |
| Model R2 | 0.22 | 0.18 | 0.07 |
| Observations | 744 | 446 | 737 |
| Log Likelihood | −2,632.5 | −1,568.5 | −2,671.4 |
| AIC | 5,292.9 | 3,162.9 | 5,370.8 |
| BIC | 5,357.5 | 3,216.2 | 5,435.2 |
Note:
*
p<0.05;
**
p<0.01;
***
p<0.001;
AIC = Akaike information criteria; BIC = Bayesian Information Criteria.
^
The intercept can be interpreted as the mean function score at T2 (event) for the reference group who are non-Hispanic white, 8-year old boys with cancer, no other health condition and a mother with education more than high school. The domain of Upper Extremity was not assessed in children with nephrotic syndrome.