Table 4.
Intensity– weighted days | Subclinical hypothyroidism | TSH and Thyroid Hormones | |||||
---|---|---|---|---|---|---|---|
| |||||||
TSH | T4 | T3 | |||||
|
|
|
|
||||
Nb | OR (95% CI) | Nc | Expβ (95% CI) | Expβ (95% CI) | Expβ (95% CI) | ||
Fumigant | |||||||
Carbon tetrachloride/ | 0 | 113 | 1.00 (ref) | 617 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
Carbon disulfided | 6–170 | 4 | 1.70 (0.51, 5.61) | 14 | 1.06 (0.76, 1.47) | 0.97 (0.85, 1.10) | 0.95 (0.82, 1.09) |
>170–18563 | 3 | 1.08 (0.29, 4.08) | 14 | 1.01 (0.73, 1.41) | 0.94 (0.82, 1.07) | 0.89 (0.77, 1.02) | |
Ptrend | 0.87 | 0.93 | 0.33 | 0.09 | |||
Methyl bromide | 0 | 117 | 1.00 (ref) | 622 | 1.00 (ref) | 1.00 (ref) | |
12–1139 | 6 | 1.32 (0.44, 4.02) | 24 | 1.31 (0.98, 1.74) | 0.89 (0.80, 1.00) | 0.94 (0.83, 1.06) | |
>1139–102000 | 3 | 0.45 (0.11, 1.81) | 26 | 0.75 (0.56, 1.00)† | 1.14 (1.01, 1.28)† | 1.11 (0.98, 1.26) | |
Ptrend | 0.23 | 0.02† | 0.01† | 0.06 | |||
Fungicide | |||||||
Captan | 0 | 103 | 1.00 (ref) | 566 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
2–12 | 3 | 0.40 (0.12, 1.35) | 36 | 0.87 (0.71, 1.07) | 1.07 (0.98, 1.17) | 1.07 (0.98, 1.16) | |
>12–46500 | 10 | 1.89 (0.87, 4.11) | 34 | 1.23 (1.00, 1.52)† | 0.99 (0.91, 1.09) | 0.99 (0.90, 1.08) | |
Ptrend | 0.09 | 0.05† | 0.87 | 0.73 | |||
Metalaxyld | 0 | 105 | 1.00 (ref) | 560 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) |
3–141 | 6 | 1.06 (0.41, 2.72) | 28 | 1.06 (0.84, 1.34) | 1.02 (0.93, 1.12) | 1.03 (0.93, 1.14) | |
>141–30341 | 4 | 0.60 (0.19, 1.92) | 28 | 0.87 (0.68, 1.12) | 1.02 (0.92, 1.13) | 0.98 (0.88, 1.09) | |
Ptrend | 0.39 | 0.27 | 0.72 | 0.67 |
TSH: Thyroid stimulating hormone; T4: thyroxine; T3: triiodothyronine
Adjusted for age, state, body mass index, smoking, correlated pesticides
Exposed cases
Total exposed
Detailed information for these chemicals was collected on the take-home questionnaire at enrollment
p<0.05 compared with never users