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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Laryngoscope. 2017 Sep 20;128(2):E59–E67. doi: 10.1002/lary.26893

Fig. 2.

Fig. 2

DON treatment of iLTS scar fibroblasts reduces collagen gene expression. DON treatment significantly reduces the expression of COL1 and COL3 in iLTS scar fibroblasts, compared to untreated iLTS scar fibroblasts. DON-treated iLTS scar fibroblast expression of COL1 and COL3 are not significantly different from normal fibroblast expression levels.

COL1 = collagen 1; COL3 = collage 3; DON = 6-diazo-5-oxo-l-norleucine; FN1 = fibronectin 1; iLTS = iatrogenic laryngotracheal stenosis; MMP 13 = matrix metallopeptidase 13; TGF β = transforming growth factor beta.