Table 1.
Demographic, lifestyle and reproductive characteristics among three cohorts of reproductive age, U.S. women.a
| Characteristics | BioCycle | EAGeR | NHANES 2005–2008b |
|---|---|---|---|
| N=259 | N=1228 | N=1507 | |
| hsCRP, mg/Lc | 0.9 (0.8, 1) | 1.3 (1.2, 1.4) | 1.4 (1.2, 1.5) |
| hsCRP, mg/Ld | 0.8 (0.4, 1.9) | 1.2 (0.6, 3.2) | 1.4 (0.4, 3.9) |
| hsCRP < 2 mg/L | 196 (75.7) | 773 (63.0) | 763 (50.6) |
| 2 ≤ hsCRP < 10 mg/L | 52 (20.1) | 370 (30.1) | 510 (40.4) |
| hsCRP ≥10 mg/L | 9 (3.5) | 63 (5.1) | 136 (9.0) |
| hsCRP missing | 2 (0.7) | 22 (1.8) | 98 (6.5) |
| Demographics | |||
| Age, y | 27.3 (26.3, 28.3) | 28.7 (28.5, 29) | 30.0 (29.5, 30.4) |
| Race: white (vs. non-white) | 154 (59.5) | 1162 (94.6) | 886 (58.8) |
| Marital status: married or living with partner | 66 (25.5) | 1199 (97.6) | 918 (60.9) |
| Education ≥ High School | 258 (99.6) | 1205 (98.1) | 1221 (81.0) |
| Annual Household Income | |||
| ≥ $75,000 | 69 (26.8) | 641 (52.2) | 345 (22.9) |
| $20,000–$74,999 | 134 (51.8) | 494 (40.2) | 867 (57.5) |
| ≤ $19,999 | 55 (21.4) | 95 (7.7) | 295 (19.6) |
| Currently employed | 211 (81.6) | 895 (72.9) | 1028 (68.2) |
| Health & Lifestyle | |||
| BMI, kg/m2 | 24.1 (23.6, 24.5) | 26.3 (26, 26.7) | 28.1 (27.5, 28.8) |
| Waist circumference, cm | 74.7 (73.7, 75.8) | 86.8 (86, 87.7) | 91.7 (90.2, 93.2) |
| Current smoker | 10 (3.9) | 151 (12.3) | 399 (26.5) |
| Physical Activity, % | |||
| Low (Walking) | 25 (9.7) | 322 (26.2) | 574 (38.1) |
| Moderate (Moderate) | 92 (35.5) | 501 (40.8) | 812 (53.9) |
| High (Vigorous) | 142 (54.8) | 405 (33.0) | 121 (8.0) |
| Sleep duration <6 hours/night | 15 (5.8) | 33 (2.7) | 217 (14.4) |
| Blood pressure, mmHg | |||
| Systolic | 99.2 (98.1, 100.3) | 111.6 (110.9, 112.3) | 110.1 (109.4, 110.9) |
| Diastolic | 61.2 (60.2, 62.2) | 72.6 (72, 73.2) | 67.4 (66.6, 68.1) |
| Pulse, bpm | 69.7 (68.7, 70.8) | 73.0 (72.3, 73.6) | 77 (76.3, 77.8) |
| Total cholesterol, mg/dLd,e | 160 (146, 176) | 163 (146, 184) | 179 (159, 202) |
| HDL cholesterol, mg/dLd,e | 49 (41, 58) | 50 (43, 58) | 55 (47, 65) |
| LDL cholesterol, mg/dL d,e | 98 (87, 116) | 99 (83, 118) | 103 (83, 124) |
| Triglycerides, mg/dL d,e | 53 (39, 72) | 100 (73, 144) | 87 (63, 126) |
| Glucose, mg/dL d,e | 87 (83, 91) | 81 (74, 88) | 92 (87, 98) |
| Insulin, μU/mL d,e | 6 (4, 8) | 11 (6, 21) | 8 (5, 13) |
| Reproductive Health History | |||
| Age at menarche, y | 12.5 (12.3, 12.6) | 12.8 (12.6, 12.9) | 12.6 (12.5, 12.7) |
| Parous | 68 (26.1) | 657 (53.5) | 1025 (68) |
| Number of live births | |||
| 0 | 191 (73.9) | 571 (46.5) | 482 (32.0) |
| 1 | 14 (5.5) | 443 (36.1) | 285 (18.9) |
| 2 | 28 (10.7) | 214 (17.4) | 404 (26.8) |
| ≥3 | 26 (9.9) | 0 (0.0) | 336 (22.3) |
| Number of pregnancies not ending in live birth | |||
| 0 | 243 (93.7) | 0 (0.0) | 1034 (68.6) |
| 1 | 16 (6.3) | 825 (67.2) | 271 (18.0) |
| 2 | 0.0 | 403 (32.8) | 118 (7.8) |
| ≥3 | 0.0 | 0 (0.0) | 84 (5.6) |
a
Data are n (%) or mean (95% confidence interval [CI]), unless otherwise noted.
b
NHANES cohort excluding women using hormonal contraception; use of hormonal contraceptives was an exclusion criteria for BioCycle and EAGeR.
c
Statistics are presented as geometric mean (95% CI).
d
Statistics are presented as median (IQR).
e
BioCycle and NHANES 2005–2008 biomarker measure is a fasting value; EAGeR is not a fasting value.