Table 3.

Average post-treatment score changes in secondary outcomes between for study participants electing continued medical therapy or cross-over to endoscopic sinus surgery

	Continued medical therapy	Treatment cross-over to ESS	Between group significance
Secondary Outcomes:	Mean [±SD]	Mean [±SD]	p-value
Endoscopy score	−2.4 [±4.0]*	−4.3 [±4.4]*	0.047
BSIT olfactory score	0.7 [±3.3]	−0.1 [±3.0]	0.328
SNOT-22 total score:	−5.0 [±20.4]*	−15.5 [±23.1]*	0.013
Rhinologic symptom score	−2.4 [±7.4]*	−5.7 [±8.0]*	0.013
Extra-nasal rhinologic score	−1.1 [±4.0]*	−1.9 [±4.1]*	0.252
Ear/facial symptom score	−0.8 [±4.8]	−1.9 [±5.4]*	0.269
Psychological dysfunction score	−1.1 [±7.3]	−4.7 [±8.0]*	0.019
Sleep dysfunction score	−0.8 [±7.1]	−5.1 [±6.2]*	0.001

ESS, endoscopic sinus surgery; SD, standard deviation; BSIT, Brief Smell Identification Test; SNOT-22, 22-item SinoNasal Outcome Test.

^*indicates significant within-subject improvement over time (p<0.050) as determined by Wilcoxon signed rank testing.