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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: Dev Dyn. 2017 Dec 4;247(2):304–314. doi: 10.1002/dvdy.24605

Fig 6. Pten deficiency increases PI3K/AKT signaling activity in neural crest cells.

Fig 6

(A–D) Immunostaining with anti phospho-AKT antibody on frontal sections of littermate control embryos (A, C) and Ptenfl/fl; Wnt1Cre2 (B, D) at E13.5. (E) Western blot using anti phospho-AKT antibody (p-Akt Ser473) and craniofacial lysates from littermate control and Ptenfl/fl; Wnt1Cre2 embryos at E13.5. (F) Quantification result and statistical analysis of western blot data on E. pmx, premaxilla; tgg, trigeminal ganglion.