a, Working model for identification of transcriptional networks enriched in TCGA tumors b, Summary of GSEA concordant findings across in cancer development and cancer progression signatures. c, Heatmap of the activity of PCSSTAp63 across different stages of tumorigenesis. d, Heatmap of the activity of PCSSΔNp63 across different stages of tumorigenesis. e, Dot plot of the survival analysis of different tumors with respect to PCSSTAp63 activity. f, Dot plot of the survival analysis of different tumors with respect to PCSSΔNp63 activity.