Figure 1.

Case #1. IgGλ MM in CR. The increasing serum IgG levels were identified as an increment either in both of the uHLC and iHLC levels (arrow case 1–1) or in the uHLC alone accompanying a decrement in the iHLC levels (arrow case 1–2) by the HLC assay. In both occasions, the HLC ratios were normal. These HLC data were interpreted as indicating a continued remission according to the diagram (Table 1). Case #2. IgGκ MM in sCR. The increasing serum IgG levels were identified as an increment in both of the uHLC and iHLC levels (arrow case 2–1) by the HLC assay. The HLC ratio became normal (arrow case 2–3) and led to the identification of continued remission according to the diagram (Table 1). Each figure shows sequential changes in total serum IgG, iHLC, and uHLC concentrations (upper frame), FLC ratios (middle frame), and HLC ratios (lower frame).