Table 5.
Sensitivity, specificity, positive predictive value, and negative predictive value for rheumatoid arthritis and asthma medications with maternal report as the reference.
| Medication | Sensitivity % (95% CI) | Specificity % (95% CI) | Positive Predictive % Value (95% CI) | Negative Predictive % Value (95% CI) |
|---|---|---|---|---|
| Rheumatoid Arthritis, n=216 | ||||
| Prednisone | 55.7 (46.5, 64.4) | 89.1 (81.5, 93.8) | 85.3 (75.6, 91.6) | 63.8 (55.6, 71.3) |
| Hydroxychloroquine | 94.2 (84.4, 98.0) | 93.9 (89.1, 96.7) | 83.1 (71.5, 90.5) | 98.1 (94.5, 99.4) |
| Sulfasalazine | 86.4 (66.7, 95.3) | 97.9 (94.8, 99.2) | 82.6 (62.9, 93.0) | 98.5 (95.5, 99.5) |
| Etanercept | 96.2 (89.4, 98.7) | 94.9 (89.8, 97.5) | 91.6 (83.6, 95.9) | 97.7 (93.6, 99.2) |
| Adalimumab | 89.5 (75.9, 95.8) | 97.2 (93.6, 98.8) | 87.2 (73.3, 94.4) | 97.7 (94.3, 99.1) |
| Ibuprofen | 37.5 (22.9, 54.8) | 92.4 (87.6, 95.4) | 10.5 (6.9, 15.7) | 89.5 (84.3, 93.1) |
| Aspirin | 42.9 (26.5, 60.9) | 96.3 (92.5, 98.2) | 63.2 (41.0, 80.9) | 91.9 (87.2, 94.9) |
|
| ||||
| Asthma, n=172 | ||||
| Prednisone | 50.0 (31.4, 68.6) | 96.6 (92.3, 98.6) | 70.6 (46.9, 86.7) | 92.3 (87.0, 95.5) |
| Fluticasone | 33.3 (17.2, 54.6) | 100 (97.5, 100) | 100 (64.6, 100) | 91.5 (86.3, 94.9) |
| Budesonide | 57.9 (36.3, 76.9) | 96.1 (91.7, 98.2) | 64.7 (41.3, 82.7) | 94.8 (90.2, 97.4) |
| Fluticasone/salmeterol | 80.8 (68.1, 89.2) | 98.3 (94.1, 99.5) | 95.5 (84.9, 98.7) | 92.2 (86.2, 95.7) |
| Budesonide/formoterol | 81.8 (61.5, 92.7) | 98.7 (95.3, 99.6) | 90.0 (69.9, 97.2) | 97.4 (93.4, 99.0) |
| Albuterol | 64.9 (56.5, 72.5) | 63.2 (47.3, 76.6) | 86.1 (78.1, 91.6) | 33.8 (23.9, 45.4) |
| Montelukast | 61.5 (42.5, 77.6) | 96.6 (92.2, 98.5) | 76.2 (54.9, 89.4) | 93.4 (88.2, 96.4) |
Abbreviation: CI, confidence interval.