Skip to main content
. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Magn Reson Med. 2017 Jul 17;79(4):2346–2358. doi: 10.1002/mrm.26831

Table 2.

Mean Parameter Values for Each Tissue Type and Model.a

Model Parameter b-Factors
[s/mm2]		 Normal PZ
(n = 56)		 Tumor PZ
(n = 27)		 Normal TZ
(n = 55)		 Tumor TZ
(n = 13)
Monoexponential ADC 0–1250 2.01 ± 0.28† 1.37 ± 0.29† 1.70 ± 0.20† 1.10 ± 0.30†
250–1250 1.71 ± 0.27† 1.14 ± 0.27† 1.39 ± 0.15† 0.89 ± 0.25†
Biexponential fslow 0–3500 0.19 ± 0.06† 0.33 ± 0.10† 0.28 ± 0.05† 0.45 ± 0.12†
250–3500 0.14 ± 0.05† 0.28 ± 0.09† 0.20 ± 0.05† 0.36 ± 0.13†
Dslow 0–3500 0.52 ± 0.11 0.41 ± 0.10*,** 0.53 ± 0.08 0.40 ± 0.11*,**
250–3500 0.40 ± 0.11 0.33 ± 0.10*,** 0.39 ± 0.06 0.29 ± 0.07*,**
Dfast 0–3500 2.81 ± 0.29 2.58 ± 0.47 2.86 ± 0.37 2.97 ± 1.34
250–3500 2.49 ± 0.34 2.09 ± 0.36* 2.21 ± 0.21* 2.01 ± 0.53*
fperfusion –   0.06 ± 0.04 0.06 ± 0.05 0.08 ± 0.04 0.07 ± 0.05
Kurtosis ADCK 0–3500 2.21 ± 0.30† 1.51 ± 0.32† 1.87 ± 0.18† 1.23 ± 0.34†
250–3500 2.06 ± 0.32† 1.36 ± 0.32† 1.67 ± 0.19† 1.05 ± 0.31†
K 0–3500 0.47 ± 0.07† 0.67 ± 0.14† 0.55 ± 0.05† 0.78 ± 0.15†
250–3500 0.48 ± 0.07† 0.67 ± 0.13† 0.55 ± 0.06† 0.77 ± 0.16†
Stretched exponential Mode 0–3500 0.89 ± 0.18† 0.56 ± 0.19† 0.74 ± 0.11† 0.41 ± 0.15†
250–3500 1.77 ± 1.06 0.90 ± 0.70* 0.98 ± 0.38* 0.69 ± 0.66*
DDC 0–3500 2.02 ± 0.29† 1.38 ± 0.36† 1.75 ± 0.20† 1.08 ± 0.35†
250–3500 25.3 ± 32.9 12.3 ± 11.9 13.2 ± 20.8 5.84 ± 7.07*
α 0–3500 0.70 ± 0.03 0.68 ± 0.05* 0.69 ± 0.03 0.66 ± 0.05*
250–3500 0.44 ± 0.06 0.45 ± 0.09 0.46 ± 0.05 0.51 ± 0.10*
Gamma distribution Mode: (k−1)·θ 0–3500 1.61 ± 0.40† 0.75 ± 0.46† 1.17 ± 0.27† 0.38 ± 0.38†
250–3500 2.74 ± 4.63 0.82 ± 0.57* 1.20 ± 0.33* 0.58 ± 0.38
k 0–3500 2.42 ± 0.61 1.65 ± 0.56* 1.90 ± 0.32* 1.32 ± 0.31*,**
250–3500 2.06 ± 0.49 1.61 ± 0.53* 1.82 ± 0.29* 1.54 ± 0.63*
θ 0–3500 1.23 ± 0.28 1.41 ± 0.43 1.37 ± 0.28 1.40 ± 0.43
250–3500 3.43 ± 7.12 1.63 ± 0.59 1.60 ± 0.58 1.52 ± 1.34
ROI Volume mm3 –   850 ± 400 630 ± 540 1920 ± 1210 800 ± 300
a

Data are given as mean ± standard deviation. Units for diffusion coefficients, θ, and Mode are μm2/ms. All significances with P < 0.05:

*

significantly different from normal appearing PZ;

**

significantly different from normal appearing TZ;

†

all four tissue types are significantly different.