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. Author manuscript; available in PMC: 2019 Mar 1.
Published in final edited form as: Hepatology. 2018 Jan 26;67(3):955–971. doi: 10.1002/hep.29371

Figure 1. Decreased liver injury in KO following BDL.

Figure 1

(A) Absent β-catenin in KO livers at 14D after BDL (100x); (B) Several bile infarcts in WT after BDL with notable absence in KO (50x); (C) Significantly fewer biliary infarcts in KO after BDL. ***p<0.001. (D) No significant differences in overall survival between WT and KO after BDL. (E) Decreased serum markers of hepatic and biliary injury in KO at 14D after BDL when compared to the WT (n=5–6 per group). *p<0.05; **p<0.01; ***p<0.001. Histology images are representative of >4 images per group. Bile infarct quantification and survival data obtained from n=8 animals/group.