Table 1.
Nest building and maternal behavior in Dio3+/+ and Dio3−/− females.
| 1st Litter | Mother’s age [days] |
Litter size | Nest score | Mothers exhibiting pup retrieval behavior |
* Latency for pup retrieval [s] |
* Time to retrieve all pups [s] |
Time spent interacting with pups [s] |
Time spent crouching over pups [s] |
Mothers exhibiting aggressive behavior towards pups |
|---|---|---|---|---|---|---|---|---|---|
| Dio3 +/+ (n=26) | 94.5 ± 2.1 | 8.8 ± 3.6 | 3.58 ± 0.09 | 24 (92%) | 15.3 ± 2.5 | 132 ± 22 | 45.5 ± 15 | 31.7 ± 11.7 | 1 (4%) |
| Dio3 −/− (n=27) | 92.6 ± 3.1 | 9.0 ± 1.9 | 3.21 ± 0.08 | 4 (15%) | 165.5 ± 98.3 | 182 ± 55 | 13.2 ± 6.6 | 9.3 ± 6.4 | 5 (19%) |
| p-value | NS | NS | < 0.01 | <0.001 | < 0.01 | NS | 0.0505 | 0.0974 | NS |
| 2nd Litter | |||||||||
| Dio3 +/+ (n=26) | 148.0 ± 3.9 | 9.7 ± 2.2 | 3.98 ± 0.09 | 24 (92%) | 15.6 ± 2.6 | 118 ± 15 | 34.8 ± 4.9 | 29.7 ± 5.0 | 1 (4%) |
| Dio3 −/− (n=23) | 166.3 ± 5.7 | 8.8 ± 3.0 | 3.76 ± 0.10 | 5 (22%) | 174 ± 56 | 108 ± 26 | 15.3 ± 11.4 | 12.4 ± 10.9 | 7 (30%) |
| p-value | < 0.05 | NS | NS | <0.001 | < 0.01 | NS | NS | NS | <0.05 |
| Hypo-thyroid (n=6) | 115.5 ± 4.9 | 10.3 ± 1.5 | 4.17 ± 0.11 | 6 (100%) | 26.7 ± 10.6 | 89 ± 13 | 77.2 ± 22.2 | 70.1 ± 25.0 | 0 (0%) |
*
Parameters of pup retrieval behavior refer only to those females actually exhibiting this behavior.