Table 1.

Clinical Stroke Manifestations.

Total Ischemic Strokes in the United States: 650,000 [5]

Number of Patients with Large Vessel Occlusion: 40–50% [5] = ~300,000

Number of LVO Patients Receiving tPA: up to 15% [6] = 45,000

Number of Patients with Recanalization from tPA: 11–40% [9, 10] = 4,950–18,00

Number of Patients Receiving Embolectomy after tPA Fails: 8,000–12,000 [5]

Number of Patients with Recanalization from embolectomy: 75% [9] = 6,000–9,000

Number of LVO Patients With Recanalization = 10,950–27,000

Number of LVO Patients Without Recanalization (i.e. Permanent Occlusion) = 273,000–289,050