Table 1.

Advantages and limitations of most commonly used non-human primates in aging research.

Species	Scientific Name	Classification	Advantages	Limitations
Grey Mouse lemur	Microcebus murinus	Prosimian	Small body size, short lifespan, interesting model for thermoregulation research	Small body size, availability, nocturnal, solitary, phylogenetic distance from humans, lack of commercially available resources
Common Marmoset	Callithrix jacchus	New World monkey	Small body size, reasonably short lifespan, short generation time, social structure, fecundity	Small body size, aging process needs further description, lack of standardized husbandry procedures, lack of commercially available resources
Squirrel monkey	Saimiri spp.	New World monkey	Small body size, somewhat realistic aging course	Long lifespan for body size, lack of commercially available resources
Macaques	Macaca sp.	Old World monkey	Well characterized, closely related to humans, large body size, realistic aging course	Long lifespan, availability of aged animals may be limited, zoonotic concerns
Vervet monkey	Chlorocebus pygerythrus	Old World monkey	Closely related to humans, large body size, realistic aging course	Long lifespan, limited availability of aged animals
Baboon	Papio hamadryas	Old World monkey	Closely related to humans, large body size, realistic aging course	Long lifespan, limited availability of aged animals, housing requirements
Chimpanzee	Pan troglodytes	Great ape	Closest human relative, realistic aging course, large body size	Long lifespan, housing requirements, imposed limitations on research, ethical considerations