Table 1.

Biochemical and clinical parameters of the 14 newborns and their mothers, who underwent paediatric evaluation and further laboratory testing.

No	Sex	C3 (μmol/L) (abnormal value < 4.31; 99th percentile)	C3/2 (abnormal value < 0.18)a	C3/C16 (abnormal value < 1.8)a	Methionine (μmol/L) (reference intervals: 4.23–44.30; 1st to 99th percentile)	Vitamin B12 (pmol/L) (reference intervals: 216–891)	Folate (nmol/L) (reference intervals: 7.0–46.5)	Hcy (μM) (abnormal value: > 10)	MMA (Mmol/mol Cr) in urine (abnormal value: > 10)	MMA (μmol/L) in serum (abnormal value: > 0.3)	Exclusively breast-fed	Mother’ s vitamin B12 (pmol/L) (reference intervals: 141–489)	Mother's prenatal folic acid supplemen-taton  ≥ 400 μg/day
1.	M	4.8	0.19	1.23	8.52	162	27.7	15.7	8.75	b	yes	251	yes
2.	M	5.27	0.3	2.17	9.01	176	38.1	6	not detected	b	yes	316	yes
3.	M	5.88	0.23	1.8	11.89	184	32	10.3	1.5	b	yes	Normal (autoimmune disease)	yes
4.	F	5.91	0.23	2.46	14.93	110	36.9	12.2	7.36	b	yes	Normal	yes
5.	F	5.96	0.08	0.47	9.09	143	31.2	22.9	62.08	6.71	yes	174	yes
6.	M	7.07	0.18	2.67	6.44	103	38.5	14.1	132	4.92	yes	Normal	yes
7.	M	7.27	0.3	2.43	6.27	60	59,9	23.6	24.07	4.0	yes	Low (vegetarian)	n.a.
8.	M	7.35	0.17	2.19	13	201	b	b	4.97	b	yes	168	yes
9.	M	7.94	0.14	1.42	20.21	184	67.2	8	2.51	17.02	yes	404	yes
10.	M	8.08	0.45	2.21	21.27	135	43	14	not detected	b	yes	Normal	yes
11.	M	8.45	0.21	2.52	8.4	187	b	b	7.7	3.19	yes	Normal	yes
12.	M	8.94	0.18	2.46	10.6	188	79	10.3	4.6	14.74	yes	246	yes
13.	M	9.91	0.17	1.52	10.7	208	35.6	11.3	9.01	2.41	yes	347	yes
14.	M	12.16	0.16	1.58	18.99	168	30.4	6.3	1.31	14.9	yes	230	yes

Biochemical and clinical parameters of the 14 newborns and their mothers, who underwent paediatric evaluation and further laboratory testing.

^aScolamiero et al.

^bNot measured.