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. 2016 Dec 16;17(1):13–18. doi: 10.1007/s12663-016-0988-1

Table 4.

Data from studies that performed histological analysis of newly formed bone by rhBMP-2

Author Lamellar bone Woven bone Trabeculate bone Vascularization Osteoblasts Osteoclasts Inflammation Collagen remants
Cochran et al. ++ +++ +++ ++ + + +
Jung et al. + +
Fiorellini et al. ++ ++ +++ + ++ +
Boyne et al. ++ + +++ ++ ++ +
Triplett et al. +++ + +++ +++ +++ + +
Marx et al. +++ + +++ +++ +++

− absent, + small amount, ++moderate amount, +++ large amount