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. 2016 Dec 16;17(1):13–18. doi: 10.1007/s12663-016-0988-1

Table 6.

Data from studies reporting adverse effects and complications in reconstructions with rhBMP-2

Author Edema Erythema Pain Immune response Systemic Infection Dehiscence/membrane exposure Total of events per study
Cochran et al. + + + + 21
Jung et al. + 1
Fiorellini et al. + + + + 250
Boyne et al. + + + + + + 546
Triplett et al. + + + NI
Freitas et al. + + + + NI
Marx et al. + + + NI
Coomes et al. + + NI
Misch et al. NI
Total studies 6 5 5 3 2 2 4 818

+ present, − absent, NI not informed