Table 4.

Cox proportional hazards regression models of Metabolic syndrome components associated with Overall and Recurrence-free survival among colorectal cancer patients.

Metabolic syndrome component	Overall Survival						Disease-free Survival
	Univariate			Multivariable			Univariate			Multivariable
	HR	95%CI	P value	HR	95%CI	P value	HR	95%CI	P value	HR	95%CI	P value
I	1.24	0.91–1.61	0.321	1.13	0.93–1.06	0.218	1.18	0.96–1.32	0.227	1.02	0.92–1.03	0.167
II	1.22	1.06–1.34	0.018*	1.12	1.00–1.24	0.021*	1.19	1.03–1.32	0.014*	1.29	1.04–1.51	0.010*
III	0.78	0.66–0.91	0.015*	0.60	0.53–0.84	0.013*	0.91	0.80–0.97	0.028*	0.83	0.75–0.93	0.035*
IV	1.23	1.11–1.52	0.041*	1.13	1.06–1.48	0.032*	1.29	1.12–1.51	0.017*	1.32	1.09–1.64	0.011*

Note: I, BMI ≥ 25 kg/m²; II, anti–hypertensive drug administration and (or) SPB ≥ 140 mmHg or DPB ≥ 90 mmHg; III, TG ≥ 1.7 mmol/L and (or) HDL < 0.9 mmol/L (male), < 1.0 mmol/L (female); IV, FPG ≥ 6.1 mmol/L or 2 h postprandial glucose ≥ 7.8 mmol/L. When perform multivariable analysis, each component was adjusted with age, CEA, stage, location, differentiation and smoking status. ^aMultivariate cox an^alysis was adjusted with age, CEA, stage, location, differentiation, metformin treatment, statin treatment and smoking status. *Represent the P value < 0.05.