Table 3.

Change from baseline to month 6 in SF-36 physical and mental component summary scores

Variable	Combination therapy: macitentan 10 mg + background therapy	Monotherapy: placebo + background therapy	Mean placebo-corrected change in scores
Change in PCS	2.8 ± 7.6	0.1 ± 7.9	2.8 (1.0–4.5)
Change in MCS	1.0 ± 11.5	− 2.1 ± 12.8	3.1 (0.3–5.8)

Data are presented as mean ± SD deviation or mean (95% confidence limit). Actelion unpublished data. A higher SF-36 score denotes better health-related quality of life (scale, 0–100)

CL confidence limit, MCS mental component summary score, PCS physical component summary score, SF-36 36-Item Short-Form survey