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. 2018 Jan 17;8:968. doi: 10.1038/s41598-018-19213-4

Figure 1.

Figure 1

Effect of erastin on the activity of various amino acid transport systems in xCT-over-expressing MEF. xCT-overexpressing MEF were cultured for 24 h and then the uptake of 0.05 mM L-[14C]cystine (Cyss), L-[14C]arginine, L-[14C]serine, and L-[14C]leucine was measured in the presence of 10 µM erastin. Bars represent the mean of percentages ± S.D. (n = 5 for cystine uptake; n = 4 for uptake of other amino acids). P values were obtained by unpaired Student’s t test. ***P = 1 × 10−6.