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. 2018 Jan 17;8:930. doi: 10.1038/s41598-017-18870-1

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Experimental protocol. (A) Experimental setup for real (REAL) and phantom (PHNT) acupuncture stimulation. In REAL, participants got stimulated in four acupoints while watching the stimulation procedure via back projection, whereas in PHNT, no afferent stimulation was given to the participants. Instead, they watched a recorded video clip of a real stimulation. (B) The acupuncture stimulation point (acupoint) locations (ST36, SP11, and r, l-SP13). (C) The event-related experimental paradigm, which consisted of five acupuncture stimulations per acupoint; each stimulation was 2 sec long, and the average inter-stimulus interval was 7.9 ± 1.7 sec. n.b. REAL, real acupuncture; PHNT, phantom acupuncture.