Table 3.
Bacteria | MOX (1g qd) (%) | MOX (1g q12h) (%) | MOX (1g q8h) (%) | MOX (2g qd) (%) | MOX (2g q12h) (%) |
---|---|---|---|---|---|
Escherichia coli ATCC25922 | 76.60 | 100 | 100 | 85.10 | 100 |
Klebsiella pneumoniae 2689 | 87.38 | 100 | 100 | 95.63 | 100 |
E. coli 3376 | 76.60 | 100 | 100 | 85.10 | 100 |
| |||||
Bacteria | MOX (2g q8h) (%) | CTX (2g qd) (%) | CTX (2g q8h) (%) | CFZ/SBT (2g qd) (%) | CFZ/SBT (2g q8h) (%) |
| |||||
E. coli ATCC25922 | 100 | 56.13 | 100 | 48.83 | 100.00 |
K. pneumoniae 2689 | 100 | 0 | 0 | 10.42 | 31.79 |
E. coli 3376 | 100 | 0 | 0 | 16.63 | 50.38 |
Abbreviations: ATCC, American Type Culture Collection; CTX, cefotaxime; CFZ, cefoperazone; MIC, minimum inhibitory concentration; MOX, moxalactam; SBT, sulbactam; %T > MIC, the time during which the concentration of the drug remained above the MIC; qd, once-daily; q12h, twice-daily; q8h, thrice-daily.