Table 3.
Sperm parameters and FISH analysis for HPV, observed at the end of the study in patients who achieved natural pregnancy, or not, from the control arm and vaccine arm.
| Sperm count (cells x 106) | Progressive Motility (%) | Normal morphology (%) | Anti-sperm antibodies (%) | HPV sperm infection (%) | HPV E.c. infection (%) | ||
|---|---|---|---|---|---|---|---|
| Control arm (N = 72) | No pregnancy (N = 61) | 106.3 ± 52.5 | 29.9 ± 12.4 | 11.0 ± 6.1 | 11.2 ± 19.9 | 7.8 ± 5.6 | 5.6 ± 5.1 |
| Pregnancy (N = 11) | 188.1 ± 99.9b | 35.2 ± 10.8b | 9.6 ± 6.2 | 7.6 ± 18.8 | 1.6 ± 4.0b | 2.8 ± 7.2 | |
| Vaccine arm (N = 79) | No pregnancy (N = 49) | 143.6 ± 124.2 | 42.3 ± 9.1a | 11.0 ± 6.1 | 5.4 ± 9.1a | 1.2 ± 2.3a | 0.6 ± 2.2a |
| Pregnancy (N = 30) | 168.7 ± 140.2 | 46.7 ± 13.7a | 10.6 ± 6.4 | 0.9 ± 3.2a | 0ab | 0.3 ± 1.1a | |
Data for FISH analysis are presented as positivity of sperm cells or exfoliated cells (E.c.).
ap < 0.05 vs control arm
bp < 0.05 vs. no pregnancy.