Table 2.
Comparison of Clinical and Ocular Characteristics between Eyes with Steeply curved LC and Relatively flat LC.
| Variables | Group 1: Steeply curved LC group (n = 75) | Group 2: Relatively flat LC group (n = 26) | P value |
|---|---|---|---|
| Demographic characteristics | |||
| Age (years) | 55.8 ± 11.4 | 61.6 ± 12.3 | 0.031 |
| Female (%) | 34 (45.3) | 9 (34.6) | 0.341 |
| Clinical characteristics | |||
| Diabetes mellitus (%) | 10 (13.3) | 4 (15.4) | 0.794 |
| Hypertension (%) | 24 (32.0) | 7 (26.9) | 0.629 |
| Cold extremities (%) | 14 (23.0) | 7 (38.9) | 0.179 |
| SBP (mmHg) | 130.1 ± 14.9 | 121.5 ± 12.7 | 0.010 |
| DBP (mmHg) | 80.2 ± 11.2 | 71.5 ± 9.1 | 0.001 |
| SPP (mmHg) | 115.1 ± 14.4 | 107.7 ± 12.0 | 0.021 |
| DPP(mmHg) | 65.1 ± 11.2 | 57.7 ± 8.8 | 0.001 |
| MAP (mmHg) | 96.8 ± 11.3 | 88.2 ± 9.4 | 0.001 |
| MPP (mmHg) | 49.5 ± 7.4 | 45.0 ± 5.8 | 0.006 |
| Ocular characteristics | |||
| Baseline IOP (mmHg) | 15.1 ± 2.7 | 13.8 ± 1.9 | 0.033 |
| Scan IOP (mmHg) | 15.3 ± 2.6 | 13.7 ± 2.0 | 0.035 |
| SE (D) | −1.33 ± 2.57 | −0.54 ± 2.63 | 0.184 |
| AXL (mm) | 24.36 ± 1.48 | 24.03 ± 1.57 | 0.373 |
| CCT (μm) | 552.6 ± 40.0 | 553.9 ± 38.9 | 0.895 |
| VF MD (dB) | −7.66 ± 7.27 | −7.40 ± 6.35 | 0.876 |
| VF PSD (dB) | 6.81 ± 4.12 | 7.16 ± 4.46 | 0.725 |
| Global RNFL thickness (μm) | 72.1 ± 15.3 | 76.4 ± 12.4 | 0.205 |
| β-PPA width (μm) | 238.4 ± 151.4 | 305.8 ± 126.5 | 0.044 |
| γ-PPA width (μm) | 61.0 ± 113.4 | 74.5 ± 162.2 | 0.644 |
| JPCT (μm) | 154.5 ± 62.9 | 105.4 ± 42.9 | <0.001 |
| Average LCCI | 11.64 ± 1.50 | 8.36 ± 0.98 | <0.001 |
| Superior midperiphery LCCI | 11.89 ± 1.88 | 8.33 ± 1.44 | <0.001 |
| Midhorizontal LCCI | 10.94 ± 2.17 | 8.08 ± 1.73 | <0.001 |
| Inferior midperiphery LCCI | 12.09 ± 2.17 | 8.67 ± 2.05 | <0.001 |
LC = lamina cribrosa; SBP = systolic blood pressure; DBP = diastolic blood pressure; SPP = systolic perfusion pressure; DPP = diastolic perfusion pressure; MAP = mean arterial pressure; MPP = mean perfusion pressure; IOP = intraocular pressure; Scan IOP = IOP at the time of optic nerve head scan; SE = spherical equivalent; D = diopter; AXL = axial length; CCT = central corneal thickness; VF = visual field; MD = mean deviation; dB = decibel; PSD = pattern standard deviation; RNFL = retinal nerve fiber layer; PPA = parapapillary atrophy; JPCT = juxtapapillary choroidal thickness, LCCI = lamina cribrosa curvature index.
Data are mean ± standard deviation values, with statistically significant P values in boldface.