Table 1.
Subject and procedures for collection of olfactory mucosa
| Genus (species) | Gender & population | Strain & Origin | Age | Anaesthesia & analgesia procedure | Collection method |
|---|---|---|---|---|---|
| Mouse (Mus musculus) | Male, 6a | C57Bl/6NCrl, Charles River Laboratories | 3 months | Euthanasia; sodium pentobarbital (Ceva Santé Animale, 200 mg/kg, i.p.) | Muzzle dissection |
| Rat (Rattus norvegicus) | Male, 6a | Fischer 344, Charles River Laboratories | 6 weeks | Sodium pentobarbital (Nembutal, 60 mg/kg, i.p.) and Buprenorphine (0.02 mg/kg i.m.) | Nasal bone trepanation |
| Rabbit (Oryctolagus cuniculus) | Male, 3 Female,3 |
Breed, IRSEA | 11 (± 1.5) months | Medetomidine (Domitor®, 0.4 mg/kg i.m.), Ketamine 100 (Imalgene®, 30 mg/kg i.m.) and Buprenorphine (0.02 mg/kg i.m.) | Nasal cavity exploration |
| Dog (Canis lupus) | Male, 4 Female, 2 | Multiple, pet dogsb | 15 (± 1) years | Zoletil (Tiletamine and Zolazepam,Virbac, 5 mg/kg i.v.) and Boutorfanole (Dolorex®, 0.1 mg/kg i.v.) | Nasal cavity exploration |
| Horse (Equus caballus) | Male, 4 | Multiple, client-ownedb | 18 (± 3) years | Détomidine (Domosedan®, 10–20 μg/kg i.v.) | Nasal cavity exploration |
| Sheep (Ovis aries) | Female, 3 | Merinos, IRSEA | 7 (± 4) years | Xylazine (Rompun® 2%, 0.04 mg/kg i.v.) | Nasal cavity exploration |
| Gray mouse Lemur (Microcebus murinus) | Male, 1 Female, 1 | CNRS Primatology centre | 7 years | Diazepam (Valium, 20 mg/kg i.m.) and Ketamine (Imalgene, 100 mg/kg i.p.) | Nasal bone trepanation |
| Macaque (Macaca fascicularis) | Male, 1 | CNRS Primatology centre | 13 years | Zoletil (Tiletamine and Zolazepam,Virbac, 5 mg/kg i.m.); then isoflurane (Belamont) | Nasal cavity exploration |
amucosa from different individuals were pooled
bclient-owned animals from veterinary clinics biopsied with owner consent