Table 1.
Main biochemical, clinical, cytological and histologic findings at diagnosis of primary differentiated thyroid cancer in 63 patients less than 30 years: comparisons between children aged from 9.7 and 17.9 years (Group A) and young adults aged from 20.0 and 29.8 years (Group B)
| Group A (n = 18) | Group B (n = 45) | p | |
|---|---|---|---|
| Biochemical picture | |||
| Euthyroidism | 72.3% | 95.6% | 0.03 |
| Overt hypothyroidism | 16.6% | 0% | 0.005 |
| Subclinical hypothyroidism | 0% | 2.2% | 0.52 |
| Overt hyperthyroidism | 11.1% | 2.2% | 0.10 |
| Clinical picture | |||
| Association with AITDsa | 33.3% | 8.9% | 0.02 |
| Cytological stagesb | |||
| III | 22.2% | 22.2% | 1.00. |
| IV | 27.8% | 33.3% | 0.67 |
| V | 27.8% | 28.9% | 0.93 |
| VI | 22.2% | 15.6% | 0.53 |
| Tumor histology | |||
| Papillary carcinoma | 55.6% | 66.7% | 0.40 |
| Papillary follicular variant | 33.3% | 31.1% | 0.86 |
| Follicular carcinoma | 11.1% | 2.2% | 0.13 |
| Risk levelsc | |||
| Low | 55.5% | 75.6% | 0.26 |
| Intermediate | 27.8% | 22.2% | 0.73 |
| High | 16.7% | 2.2% | 0.03 |
aAutoimmune thyroid diseases
bAccording to the Bethesda system (Reference No. 14)
cAccording to the staging system described by Francis et al. (Reference No.10)