Table 2.
Spearman rank correlation between serum PCSK9 and different covariates in groups with different glucose tolerance
| All (n = 600) |
NGT (n = 200) |
IGR (n = 200) |
T2DM (n = 200) |
|||||
|---|---|---|---|---|---|---|---|---|
| r | p | r | p | r | p | r | p | |
| Age(years) | 0.086 | 0.035 | 0.105 | 0.138 | 0.113 | 0.112 | 0.034 | 0.629 |
| SBP(mmHg) | 0.113 | 0.006 | −0.074 | 0.297 | 0.202 | 0.004 | −0.012 | 0.866 |
| DBP(mmHg) | 0.016 | 0.695 | −0.087 | 0.219 | −0.007 | 0.922 | −0.077 | 0.278 |
| BMI(kg/m2) | 0.180 | <0.001 | 0.109 | 0.126 | 0.146 | 0.039 | 0.101 | 0.157 |
| WC(cm) | 0.131 | 0.001 | 0.068 | 0.343 | 0.051 | 0.476 | 0.094 | 0.190 |
| HC(cm) | 0.101 | 0.014 | 0.153 | 0.032 | 0.048 | 0.503 | 0.025 | 0.729 |
| WHR | 0.103 | 0.013 | −0.028 | 0.701 | 0.038 | 0.590 | 0.120 | 0.095 |
| HR | 0.174 | <0.001 | 0.171 | 0.016 | 0.101 | 0.153 | 0.039 | 0.582 |
| HDL-C(mmol/L) | −0.042 | 0.309 | −0.025 | 0.729 | 0.071 | 0.314 | −0.038 | 0.590 |
| LDL-C(mmol/L) | 0.192 | <0.001 | 0.194 | 0.006 | 0.201 | 0.004 | 0.145 | 0.040 |
| TC(mmol/L) | 0.134 | 0.001 | 0.100 | 0.159 | 0.164 | 0.021 | 0.136 | 0.055 |
| TG(mmol/L) | 0.165 | 0.001 | 0.047 | 0.505 | 0.055 | 0.443 | 0.166 | 0.019 |
| FBG(mmol/L) | 0.266 | <0.001 | −0.008 | 0.915 | −0.039 | 0.583 | 0.223 | 0.001 |
| 2-hPG(mmol/L) | 0.426 | <0.001 | 0.215 | 0.002 | 0.512 | 0.001 | 0.323 | <0.001 |
| FINS(μIU/ml) | 0.249 | <0.001 | 0.096 | 0.175 | 0.214 | 0.002 | 0.243 | 0.001 |
| 2 h–INS(μIU/ml) | 0.231 | <0.001 | 0.149 | 0.035 | 0.306 | <0.001 | −0.007 | 0.916 |
| HOMA-IR | 0.294 | <0.001 | 0.099 | 0.163 | 0.176 | 0.013 | 0.312 | <0.001 |
SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, WC waist circumference, HC hip circumference, WHR waist-to-hip ratio, HR heart rate, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TC total cholesterol, TG triglyceride, FBG fasting bloodglucose, 2-hPG 2-h postchallenge plasma glucose, FINS fasting insulin, 2 h–INS 2-hpostchallenge plasma insulin, PCSK9 Preproteinconvertasesubtilisin/kexin type 9, HOMA-IR homeostasis model assessment-estimated insulin resistance index
ap < 0.05, bp < 0.01