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. 2018 Jan 17;17:15. doi: 10.1186/s12944-018-0658-z

Table 2.

Spearman rank correlation between serum PCSK9 and different covariates in groups with different glucose tolerance

All
(n = 600)
NGT
(n = 200)
IGR
(n = 200)
T2DM
(n = 200)
r p r p r p r p
Age(years) 0.086 0.035 0.105 0.138 0.113 0.112 0.034 0.629
SBP(mmHg) 0.113 0.006 −0.074 0.297 0.202 0.004 −0.012 0.866
DBP(mmHg) 0.016 0.695 −0.087 0.219 −0.007 0.922 −0.077 0.278
BMI(kg/m2) 0.180 <0.001 0.109 0.126 0.146 0.039 0.101 0.157
WC(cm) 0.131 0.001 0.068 0.343 0.051 0.476 0.094 0.190
HC(cm) 0.101 0.014 0.153 0.032 0.048 0.503 0.025 0.729
WHR 0.103 0.013 −0.028 0.701 0.038 0.590 0.120 0.095
HR 0.174 <0.001 0.171 0.016 0.101 0.153 0.039 0.582
HDL-C(mmol/L) −0.042 0.309 −0.025 0.729 0.071 0.314 −0.038 0.590
LDL-C(mmol/L) 0.192 <0.001 0.194 0.006 0.201 0.004 0.145 0.040
TC(mmol/L) 0.134 0.001 0.100 0.159 0.164 0.021 0.136 0.055
TG(mmol/L) 0.165 0.001 0.047 0.505 0.055 0.443 0.166 0.019
FBG(mmol/L) 0.266 <0.001 −0.008 0.915 −0.039 0.583 0.223 0.001
2-hPG(mmol/L) 0.426 <0.001 0.215 0.002 0.512 0.001 0.323 <0.001
FINS(μIU/ml) 0.249 <0.001 0.096 0.175 0.214 0.002 0.243 0.001
2 h–INS(μIU/ml) 0.231 <0.001 0.149 0.035 0.306 <0.001 −0.007 0.916
HOMA-IR 0.294 <0.001 0.099 0.163 0.176 0.013 0.312 <0.001

SBP systolic blood pressure, DBP diastolic blood pressure, BMI body mass index, WC waist circumference, HC hip circumference, WHR waist-to-hip ratio, HR heart rate, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, TC total cholesterol, TG triglyceride, FBG fasting bloodglucose, 2-hPG 2-h postchallenge plasma glucose, FINS fasting insulin, 2 h–INS 2-hpostchallenge plasma insulin, PCSK9 Preproteinconvertasesubtilisin/kexin type 9, HOMA-IR homeostasis model assessment-estimated insulin resistance index

ap < 0.05, bp < 0.01