Fig. 1.

Worldwide relative search volume of queries related to sepsis. Hashed vertical lines represent points at which local time trends were found to change. Outlying weeks and the adjusted time series were generated from the final autoregressive model incorporating transfer functions. Outlying values in the adjusted series have been replaced with those predicted by the final model to highlight the extent of deviation from the modeled baseline. Sepsis was queried as a topic as described in the Methods