Table 1.

Individual outlying epochs with relative search volume above the modeled baseline

Week	RSV	Effect duration in weeks (impact per week)	Potential awareness and media correlates	p value (per week)
Individual positive outlying epochs
8 July 2012	52	1 (+3.25)	Pediatric sepsis death in the USA	< 0.0001
11 November 2012	59	1 (+15.95)	Adult death following septic miscarriage in Ireland	< 0.0001
30 November 2014	62	1 (+14.05)	Adult deaths from sepsis secondary to contaminated sharps in India	< 0.0001
11 January 2015	57	1 (+8.26)	Adult sepsis death in the USA	0.0002
24 January 2016	80	1 (+26.0)	NHS report on, and wide coverage of, a pediatric sepsis death in the UK	< 0.0001
27 March 2016	93	3 (+36.86, +6.04, +5.53)	Death of Patty Duke from abdominal sepsis in the USA	< 0.0001, 0.0068, 0.0135
29 May 2016	69	2 (+13.83, +44.66)	Death of Muhammad Ali	< 0.0001, < 0.0001
11 September 2016	84	3 (+18.36, +10.16, +8.33)	Inaugural World Sepsis Congress, fifth World Sepsis Day with international coverage, US CDC awareness efforts	< 0.0001, < 0.0001, 0.0004
2 October 2016	72	1 (+10.95)	Adult sepsis death in the UK	< 0.0001
1 January 2017	68	1 (+7.0)	Pediatric sepsis death in the USA	0.0012
19 February 2017	70	1 (+6.24)	Multiple news media correlates	0.0049
5 March 2017	73	1 (+8.18)	NHS sepsis 1-hour intervention mandate in the UK	0.0003
19 March 2017	72	1 (+6.41)	Coverage of vitamin C as a potential therapeutic intervention	0.0042
26 March 2017	81	1 (+16.03)	Additional vitamin C coverage, NHS apology regarding pediatric sepsis death	< 0.0001
Starting year	Week	Impact coefficient	Potential correlates
Cyclic outlying effects
2012	37	+7.82	World Sepsis Day	< 0.0001
2012	51	–2.82	Holiday season	0.0042
2012	52	–7.60		< 0.0001

CDC Centers for Disease Control, NHS National Health Service, RSV relative search volume