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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Int J Eat Disord. 2017 Aug 18;50(10):1194–1204. doi: 10.1002/eat.22767

Fig. 1. Experimental timeline, body weight, and feeding test data.

Fig. 1

Systemic injections of the CRF1 receptor antagonist R121919 but not metyrapone decreased frustration stress-induced binge eating in rats with a history of intermittent food restriction. (A) Timeline of the experimental procedures for the food non-restricted (top) and restricted (bottom) rats. (B) Mean ± SEM palatable food intake (kcal/kg) during the first 15 min (left) and the cumulative 2 h (right) test session. *p < 0.05; **p < 0.01, different from the vehicle condition; #p < 0.05; ##p < 0.01, different from the other three vehicle groups. n = 6–8 per group. (C) Mean ± SEM palatable food intake (kcal/kg) during the first 15 min (left) and the cumulative 2 h (right) test. #p < 0.05; ##p < 0.01, different from the non-restricted and non-stressed group. n = 6–8 per group.