Table 2.
Correlation between histological subtypes and clinical and CT imaging characteristics
| Variable | AIS/MIA(124) | IA(269) | p value |
|---|---|---|---|
| Gender | 0.984 | ||
| Male | 37 | 80 | |
| Female | 87 | 189 | |
| Median age | 55.85 ± 9.42 | 58.49 ± 9.00 | 0.008* |
| Smoking | 0.246 | ||
| Current/ever | 98 | 198 | |
| Never | 26 | 71 | |
| History of family cancer | 0.046* | ||
| Yes | 45 | 71 | |
| No | 79 | 198 | |
| CEA | 1.5 (1.0,2.4) | 2.1 (1.3,3.1) | 0.000* |
| CA19–9 | 11.0 (8.4,17.4) | 9.4 (6.5,15.3) | 0.081 |
| Location of tumor | 0.084 | ||
| RUL | 52 | 111 | |
| RML | 8 | 12 | |
| RLL | 15 | 50 | |
| LUL | 39 | 59 | |
| LLL | 10 | 37 | |
| GGO size | 1.2 (0.8,1.6) | 2.0 (1.6,2.5) | 0.000* |
| GGO type | 0.000* | ||
| pGGO | 90 | 77 | |
| mGGO | 34 | 192 | |
| Air bronchogram | 18 | 71 | 0.074 |
| Bubble-like sign | 22 | 92 | 0.001* |
| Spicule sign | 32 | 79 | 0.140 |
| Pleural tag | 31 | 71 | 0.163 |
| Pathological stage | 0.000* | ||
| 0/IA | 124 | 255 | |
| IB | 0 | 14 | |
| Lymphatic metastasis | – | – | – |
*Statistically significant p value, CEA carcinoembryonic antigen, CA19–9 carbohydrate antigen 19–9, pGGO pure ground-glass opacity nodule, mGGN mixed ground-glass opacity nodule, RUL superior lobe of right lung, RML middle lobe of right lung, RLL inferior lobe of right lung, LUL superior lobe of left lung, LLL inferior lobe of left lung