Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 9;15(1):741–746. doi: 10.3892/ol.2017.7376

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Rui et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 3. — Inhibition of CTLA-4 expression promoted CIK cell expansion in vitro. CIK cells on day 10 were transduced with shCTLA-4 lentiviral particles, shControl lentiviral particles, or mock transduced. A total of 96 h after cell transduction, CIK cells were harvested and counted to evaluate cell expansion efficiency. (A) CIK cells mock transduced (left panel), transduced with shControl lentiviral particles (middle panel), or transduced with shCTLA-4 lentiviral particles (right panel). Magnification, ×40. (B) Compared with mock transduced CIK cells or shControl lentiviral particles transduced CIK cells, shCTLA-4 lentiviral particles transduced CIK cells exhibited a higher expansion rate. *P<0.01. Each experiment was performed three times. The data are plotted as the mean ± standard error of the mean. CTLA-4, cytotoxic T lymphocyte-associated antigen 4; CIK, cytokine-induced killer; PMBC, peripheral blood mononuclear cells; qPCR, quantitative polymerase chain reaction; sh, short hairpin.